I went through a spike hyzer approach stage a few years back when I first started playing, and the spike is still my favorite shot to make. For a long time I didn't think it was possible to throw a golf disc on a straight flat line, I would always look for the big hyzer line, even if it was 50 or 100 feet out of the way, over a giant tree, etc.
This changed when I started throwing an ultimate with my friends every day and concentrating on getting a solid wrist snap, trying to get the ultimate to hold a flat line for the entire flight, getting it to float in the air as long as possible, just generating tons of spin. This helped, and I bought a Classic Roc, which was the first disc I could throw flat for the entire flight (a very underrated disc if you ask me).
Now, even though I'm fairly accurate with them, I only throw spikes when absolutely necessary. I figured the shortest distance between two points is a straight line, so less time in the air = less chance for flight to get screwed up by wind.